CARDACE (Ramipril) 2.5mg

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Cardace Brand is Manufactured by Aventis Pharma

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CARDACE (Ramipril) 2.5mg

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What is Cardace (Ramipril)?
Cardace (Ramipril) is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme.Cardace (Ramipril) is used to treat high blood pressure (hypertension) or congestive heart failure, and to improve survival after a heart attack.Cardace (Ramipril) may also be used for other purposes not listed in this medication guide.


Important information about Cardace (Ramipril)
Do not use Cardace (Ramipril) if you are pregnant. Stop using this medicine and tell your doctor right away if you become pregnant. Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of Cardace (Ramipril). Do not use salt substitutes or potassium supplements while taking Cardace (Ramipril), unless your doctor has told you to.Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking Cardace (Ramipril), which can lead to severely low blood pressure or a serious electrolyte imbalance.Your blood pressure will need to be checked often. Your kidney or liver function may also need to be tested. Visit your doctor regularly.If you need surgery, tell the surgeon ahead of time that you are using Cardace (Ramipril). You may need to stop using the medicine for a short time.If you are being treated for high blood pressure, keep using Cardace (Ramipril) even if you feel fine. High blood pressure often has no symptoms.


Before taking Cardace (Ramipril)
You should not use Cardace (Ramipril) if you are allergic to ramipril or to any other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), or trandolapril (Mavik).If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Cardace (Ramipril):kidney disease (or if you are on dialysis);liver disease;diabetes;a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis;if you are also taking telmisartan (Micardis); orif you have ever had a severe allergic reaction.FDA pregnancy category D. Do not use Cardace (Ramipril) if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant. Cardace (Ramipril) can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control while taking this medicine. Ramipril can pass into breast milk and may harm a nursing baby. You should not breast-feed while taking Cardace (Ramipril).


How should I take Cardace (Ramipril)?
Take Cardace (Ramipril) exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.Your doctor may occasionally change your dose to make sure you get the best results.Cardace (Ramipril) can be taken with or without food.Swallow the tablet whole.You may open the Cardace (Ramipril) capsule and sprinkle the medicine into a half-cup (4 ounces) of water, apple juice, or applesauce to make swallowing easier. Swallow without chewing. You may store the mixture for up to 24 hours at room temperature, or up to 48 hours in a refrigerator.Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking Cardace (Ramipril), which can lead to severely low blood pressure or a serious electrolyte imbalance.To be sure Cardace (Ramipril) is helping your condition, your blood pressure will need to be checked often. Your kidney or liver function may also need to be tested. Visit your doctor regularly.If you need surgery, tell the surgeon ahead of time that you are using Cardace (Ramipril). You may need to stop using the medicine for a short time.If you are being treated for high blood pressure, keep using Cardace (Ramipril) even if you feel fine. High blood pressure often has no symptoms.
 


Store Cardace (Ramipril) at room temperature away from moisture and heat.


What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention .Overdose symptoms may include feeling extremely dizzy or light-headed, or fainting.


What should I avoid while taking Cardace (Ramipril)?
Avoid drinking alcohol. It can further lower your blood pressure and may increase some of the side effects of Cardace (Ramipril). Do not use salt substitutes or potassium supplements while taking Cardace (Ramipril), unless your doctor has told you to.Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.


Side effects of Cardace (Ramipril)  
Get emergency medical help if you have any of these signs of an allergic reaction to Cardace (Ramipril): hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:feeling like you might pass out;dry mouth, thirst, confusion, swelling, and urinating less than usual or not at all;fever, chills, body aches, flu symptoms, sores in your mouth and throat;easy bruising or bleeding;pale skin, dark colored urine, fever, confusion or weakness.jaundice (yellowing of the skin or eyes); orchest pain.
Less serious Cardace (Ramipril) side effects may include:
cough;tired feeling, headache;dizziness, spinning sensation; ornausea, vomiting.This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. 


What other drugs will affect Cardace (Ramipril)?
Tell your doctor about all other medicines you use, especially:a diuretic (water pill);gold injections to treat arthritis;lithium (Lithobid, Eskalith);a potassium supplement such as K-Dur, Klor-Con;salt substitutes that contain potassium; oraspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), naproxen (Aleve, Naprosyn), and others.This list is not complete and other drugs may interact with Cardace (Ramipril). Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



Generic Name Ramipril
Search Name Altace /Tritace 2.5mg Tab
Supply Name CARDACE
Brand Generic BRAND NAME
Presentation Foil
Dosage Tab
USA Brand Altace /Tritace
Manufacture Aventis Pharma India
Strength 2.5mg
Search Terms Altace /Tritace,CARDACE,Ramipril
Origin India

Use spaces to separate tags. Use single quotes (') for phrases.

FOR THE CONSUMER

Along with its needed effects, ramipril may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ramipril:

More common:
-Blurred vision
-confusion
-dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
-sweating
-unusual tiredness or weakness

Less common:
-Arm, back, or jaw pain
-chest pain or discomfort
-chest tightness or heaviness
-chills
-cloudy urine
-cold sweats
-decrease in urine output or decrease in urine-concentrating ability
-fainting
-fast or irregular heartbeat
-nausea
-shortness of breath

Some side effects of ramipril may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common:
-Cough

Less common:
-Diarrhea
-feeling of constant movement of self or surroundings
-sensation of spinning
-vomiting
USUAL ADULT DOSE FOR DIABETIC NEPHROPATHY
Initial dose: 2.5 mg orally once a day for patients not receiving a diuretic
Maintenance dose: 2.5 to 20 mg/day orally in 1 to 2 divided doses

USUAL ADULT DOSE FOR HYPERTENSION
Initial dose: 2.5 mg orally once a day for patients not receiving a diuretic
Maintenance dose: 2.5 to 20 mg/day orally in 1 to 2 divided doses

USUAL ADULT DOSE FOR CONGESETIVE HEART FAILURE
Initial dose: 2.5 mg orally twice a day
Maintenance dose: 5 mg orally twice a day

USUAL ADULT DOSE FOR LEFT VENTRICULE DYSFUNCTION
Initial dose: 2.5 mg orally twice a day
Maintenance dose: 5 mg orally twice a day

USUAL ADULT DOSE FOR MYOCARDIAL INFARCTION
Initial dose: 2.5 mg orally twice a day
Maintenance dose: 5 mg orally twice a day

RENAL DOSE ADJUSTMENTS
CrCl less than 40 mL/min:
Initial dose: 1.25 mg orally once a day.
Dosage may be titrated upward until blood pressure is controlled or to a maximum total daily dose of 5 mg.
CrCl less than 10 mL/min:
The dose should be reduced by 25% to 50% of the normal dose.

DOSE ADJUSTMENTS
The antihypertensive effect may diminish toward the end of the dosing interval. In such patients, an increase in dosage or twice daily administration should be considered.
Heart Failure patients who become hypotensive at the 2.5 mg dose may be switched to 1.25 mg twice a day, but all patients should then be titrated (as tolerated) toward the 5 mg twice a day target dose.

PRECAUTIONS
In patients who are currently being treated with a diuretic, symptomatic hypotension occasionally can occur following the initial dose of ramipril. To reduce the likelihood of hypotension, the diuretic should, if possible, be discontinued 2 to 3 days prior to beginning therapy with ramipril. Then, if blood pressure is not controlled with ramipril alone, diuretic therapy should be resumed. If the diuretic cannot be discontinued, an initial dose of 1.25 mg ramipril should be used to avoid excess hypotension.
Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

OTHER COMMENTS
If blood pressure is not controlled with ramipril alone, a diuretic can be added.
Compared with Caucasian patients, Black patients have a reduced blood pressure response to monotherapy with angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers; however, the reduced response is largely eliminated if combination therapy that includes an adequate dose of a diuretic is instituted.
Following first time MI, all ACE inhibitors, at comparable appropriate dosages, appear to be equally effective for reducing mortality and recurrent MI rates.