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How does Diamicron MR (Gliclazide MR) work? What will it do for me?
Gliclazide MR is an oral hypoglycemic medication used for the control of blood glucose in people with type 2 diabetes. It is used when diet, exercise, and weight reduction have not been found to control blood glucose well enough on their own. Gliclazide MR increases the amount of insulin released by the pancreas and helps the body use insulin more efficiently.Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here.If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.Do not give this medication to anyone else, even if they have the same symptoms as you do.It can be harmful for people to take this medication if their doctor has not prescribed it.
How should I use this medication?
The recommended dose of gliclazide MR ranges from 30 mg to 120 mg once daily. It is recommended that the medication be taken at breakfast time. Swallow the tablet whole; do not chew or crush.Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.Keep this medication out of the reach of children.Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Who should NOT take this medication?
Gliclazide MR should not be taken by anyone who:is allergic to gliclazide MR is in a state of ketoacidosis (high ketones in urine) is pregnant is undergoing surgery or has suffered from recent severe trauma has poor blood glucose (this medication should not be taken as the only antidiabetes medication - people with type 1 diabetes should be treated with insulin) has reduced kidney or liver function has serious infection
What side effects are possible with this medication?
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.changes in taste sensation changes in appetite (increased or decreased) constipation diarrhea difficulty focusing eyes dizziness frequent urination gas in stomach heartburn increased amounts of urine increased skin sensitivity to the sun nausea or vomiting stomach pain or discomfort Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.Check with your doctor as soon as possible if any of the following side effects occur:
unusual weight gain symptoms caused by low blood sugar: anxiousness feeling drunk blurred vision cold sweats confusion difficulty concentrating drowsiness hunger fast heart rate headache nausea nervousness nightmares shakiness slurred speech unusual tiredness
itching or rash peeling of skin reddening of skin Rare chest pain coughing up blood shortness of breath sore throat thinning of skin unusual bleeding or bruising unusual tiredness yellowing of eyes or skin Seek immediate medical attention if any of the following occur:back pain headache increased blood pressure respiratory infections seizures unconsciousness urinary tract infections Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Precautions or warnings for this medication?
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.Alcohol use: Gliclazide MR can cause an unpleasant "intolerance reaction" to alcohol. People taking gliclazide MR may experience flushing, warmth, nausea, giddiness, and possibly increased heart rate when they use alcohol. To prevent this reaction, the use of alcohol should be avoided.Diabetes complications: The use of gliclazide MR (or any other medication used for diabetes) will not prevent the development of diabetes complications.Hypoglycemia (low blood sugar): As with other sulfonylurea medications like gliclazide MR, symptoms of hypoglycemia (low blood sugar) including dizziness, lack of energy, drowsiness, headache, and sweating have been observed. Weakness, nervousness, shakiness, and numbness or tingling have also been reported. Severe hypoglycemia can result from taking any of the sulfonylurea medications.The elderly, those with reduced liver or kidney function, and those who are fragile or malnourished are more likely to have low blood sugar when they take these medications. Low blood sugar is more likely to occur when food intake is inadequate or after strenuous or prolonged physical exercise. Blood glucose should be monitored regularly and emergency glucose (and glucagon kit) kept available in case the need arises to increase blood sugar levels.Illness/stress: People on gliclazide MR therapy may experience loss of blood sugar control during illness or stressful situations, such as trauma or surgery. Under these conditions, the doctor may give consideration to stopping the medication and prescribing insulin until the situation improves.Proper diet: The use of gliclazide MR must be considered as treatment in addition to proper diet and not as a substitute for diet.Worsening of condition: Over a period of time, gliclazide MR may become less effective because of the worsening of diabetes. If gliclazide MR no longer controls blood glucose to target levels, it should be stopped and another medication added.
Pregnancy: Gliclazide MR should not be taken by pregnant women.
Breast-feeding: Some sulfonylurea medications like gliclazide MR are excreted in breast milk, but it is not known whether gliclazide MR is one of them. Because the potential for low blood sugar in nursing infants may exist, a decision should be made whether to discontinue breast-feeding or to discontinue the medication, taking into account the importance of the medication to the mother.
Children: The safety and effectiveness of using this medication have not been established for children.
What other drugs could interact with this medication?
There may be an interaction between gliclazide MR and any of the following:
ACE inhibitors (e.g., enalapril) diuretics (e.g., thiazides, furosemide) alcohol anticoagulants (e.g., warfarin, heparin) azole antifungal medications (e.g., miconazole, clotrimazole) barbiturates (e.g., phenobarbital, thiopental) beta-blockers (e.g., metoprolol, propranolol) chlorpromazine corticosteroids (e.g., prednisone) disopyramide fibrates (e.g., clofibrate) H2 receptor antagonists (e.g., ranitidine, famotidine, cimetidine) monoamine oxidase inhibitors (MAOIs; e.g., selegiline, phenelzine) nicotinic acid nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., ibuprofen, naproxen) oral contraceptives other antidiabetes medications (e.g., insulin, metformin) phenylbutazone probenecid salbutamol salicylates (e.g., ASA) terbutaline If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:stop taking one of the medications, change one of the medications to another, change how you are taking one or both of the medications, or leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
|Search Name||Diamicron MR Brand 60mg TAB|
|Supply Name||DIAMICRON MR|
|Brand Generic||BRAND NAME|
|Presentation||Foil in Pharmacy Box|
|USA Brand||Diamicron MR|
|Search Terms||Diamicron MR ,DIAMICRON MR ,Gliclazide|