Thyronorm (levothyroxine sodium ) 25mcg

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Thyronorm (levothyroxine sodium ) 25mcg

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What is Thyronorm (levothyroxine sodium ) ?
Thyronorm (levothyroxine sodium )is a replacement for a hormone that is normally produced by your thyroid gland to regulate the body's energy and metabolism. Thyronorm (levothyroxine sodium )is given when the thyroid does not produce enough of this hormone on its own.Thyronorm (levothyroxine sodium )treats hypothyroidism (low thyroid hormone). Thyronorm (levothyroxine sodium )is also used to treat or prevent goiter (enlarged thyroid gland), which can be caused by hormone imbalances, radiation treatment, surgery, or cancer. It should not be used to treat obesity or weight problems.Thyronorm (levothyroxine sodium )may also be used for other purposes not listed in this medication guide.


Important information about Thyronorm (levothyroxine sodium ) 
Since thyroid hormone occurs naturally in the body,almost anyone can take Thyronorm (levothyroxine sodium ) .You should not use this medication if you have had a heart attack, a thyroid disorder called thyrotoxicosis, or an adrenal gland problem that is not controlled by treatment.
Before taking Thyronorm (levothyroxine sodium ),tell your doctor if you have heart disease, coronary artery disease, anemia (lack of red blood cells), diabetes, problems with your pituitary or adrenal glands, or a history of blood clots.If you use insulin or take diabetes medicine by mouth, ask your doctor if your dose needs to be changed when you start using Thyronorm (levothyroxine sodium ) .Different brands of levothyroxine may not work the same. If you get a prescription refill and your new pills look different, talk with your pharmacist or doctor.It may take several weeks before your body starts to respond to this medication. Do not stop taking this medication suddenly. Even if you feel well, you may still need to take this medicine every day for the rest of your life to replace the thyroid hormone your body cannot produce.There are many other medicines that can affect Thyronorm (levothyroxine sodium ) . Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.


Before taking Thyronorm (levothyroxine sodium ) Since thyroid hormone occurs naturally in the body, almost anyone can take Thyronorm (levothyroxine sodium ) . You should not use this medication if you have had a heart attack, a thyroid disorder called thyrotoxicosis, or an adrenal gland problem that is not controlled by treatment.Before taking Thyronorm (levothyroxine sodium ) , tell your doctor if you have heart disease, coronary artery disease, anemia (lack of red blood cells), diabetes, problems with your pituitary or adrenal glands, or a history of blood clots.If you use insulin or take diabetes medicine by mouth, ask your doctor if your dose needs to be changed when you start using Thyronorm (levothyroxine sodium ) .Thyronorm (levothyroxine sodium )  is in the FDA pregnancy category A. This means that it is safe to use while you are pregnant. It is also safe to use while you are breast-feeding a baby. This drug does pass into breast milk, but it is not expected to be harmful to a nursing infant.Tell your doctor if you become pregnant during treatment. You may need to increase your dose during pregnancy or if you plan to breast-feed.In most cases, you will need to take Thyronorm (levothyroxine sodium )  for the rest of your life. Taking Thyronorm (levothyroxine sodium )  over long periods of time may cause bone loss, which can lead to osteoporosis. Talk with your doctor about how this could affect you.


How should I take Thyronorm (levothyroxine sodium ) ?
Take Thyronorm (levothyroxine sodium )  exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.Your doctor may occasionally change your dose to make sure you get the best results from this medication.It is very important to take Thyronorm (levothyroxine sodium )  with a full glass (8 ounces) of water. The Thyronorm (levothyroxine sodium )  tablet can dissolve very quickly and swell in the throat, possibly causing choking or gagging. Take this medicine on an empty stomach, 30 minutes before eating. Thyronorm (levothyroxine sodium )  is usually taken in the morning. Follow your doctor's dosing instructions and try to take this medication at the same time each day.It may take several weeks before your body starts to respond to Thyronorm (levothyroxine sodium ) . Do not stop taking this medication suddenly. Even if you feel well, you may still need to take this medicine every day for the rest of your life to replace the thyroid hormone your body cannot produce.To be sure Thyronorm (levothyroxine sodium )  is helping your condition, your blood will need to be tested often. Your liver or kidney function may also need to be tested. Visit your doctor regularly.Tell any doctor or dentist who treats you that you are using Thyronorm (levothyroxine sodium ) .


Store Thyronorm (levothyroxine sodium )  at room temperature away from moisture and heat.


What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?
Seek emergency medical attention.Overdose symptoms may include chest pain, pounding heartbeat, tremor, shortness of breath, leg cramps, confusion, vomiting, diarrhea, or seizures.


What should I avoid while taking Thyronorm (levothyroxine sodium ) ?
Do not change brands or change to a generic levothyroxine drug product without first asking your doctor. Different brands of levothyroxine may not work the same. If you get a prescription refill and your new pills look different, talk with your pharmacist or doctor.Avoid the following food products, which can make your body absorb less Thyronorm (levothyroxine sodium ) : infant soy formula, cotton seed meal, walnuts, and high-fiber foods.


Side effects of Thyronorm (levothyroxine sodium )  
Stop using Thyronorm (levothyroxine sodium )  and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:headache;sleep problems (insomnia);nervous or irritable feeling;fever, hot flashes, sweating;changes in your menstrual periods;appetite changes, weight changes;
Less serious Thyronorm (levothyroxine sodium )  side effects may include mild hair loss.


What other drugs will affect Thyronorm (levothyroxine sodium ) ?
The following drugs may cause medical problems if you use them with Thyronorm (levothyroxine sodium ) : lithium, amiodarone, or antidepressants. Tell your doctor if you have recently received radiation therapy with iodine (such as I-131).This list is not complete and there are many other drugs that can interact with Thyronorm (levothyroxine sodium ) . Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.Certain medicines can be continued, but they may make Thyronorm (levothyroxine sodium )  less effective if taken at the same time. If you use any of the following drugs, use them at least 4 hours before or 4 hours after you take Thyronorm (levothyroxine sodium ) :calcium carbonate (Caltrate, Citracal, Oystercal, and others);ferrous sulfate iron supplement;sucralfate (Carafate);sodium polystyrene sulfonate (Kayexalate, Kionex, and others);antacids that contain aluminum (Amphojel, Gaviscon, Maalox, Mylanta, Riopan, Rulox, Tums, and others); andcholesterol-lowering drugs cholestyramine (Questran) and colestipol (Colestid).



Generic Name levothyroxine sodium
Search Name Synthroid Brand 25mcg Tab
Supply Name Thyronorm
Brand Generic BRAND NAME
Presentation Glass Bottle
Dosage Tab
USA Brand Synthroid
Manufacture ABBOTT
Strength 25mcg
Search Terms Synthroid ,Thyronorm ,levothyroxine sodium
Origin India

Use spaces to separate tags. Use single quotes (') for phrases.

For the Consumer

Applies to levothyroxine: oral capsule liquid filled, oral tablet

Other dosage forms:

injection powder for solution
Along with its needed effects, levothyroxine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking levothyroxine:

Less common
- Chest pain or discomfort
- decreased urine output
- difficult or labored breathing
- difficulty with swallowing
- dilated neck veins
- extreme fatigue
- fainting
- fast, slow, irregular, pounding, or racing heartbeat or pulse
- fever
- heat intolerance
- hives or welts
- increased blood pressure
- increased pulse
- irregular breathing
- irritability
- menstrual changes
- nausea
- pain or discomfort in the arms, jaw, back, or neck
- shortness of breath
- skin itching, rash, or redness
- sweating
- swelling of the eyes, face, lips, throat, or tongue
- tightness in the chest
- tremors
- troubled breathing

Rare
- Blurred or double vision
- dizziness
- eye pain
- lack or slowing of normal growth in children
- limp or walk favoring one leg
- pain in the hip or knee
- seizures
- severe headache

Get emergency help immediately if any of the following symptoms of overdose occur while taking levothyroxine:

Symptoms of overdose
- Change in consciousness
- cold, clammy skin
- confusion
- disorientation
- fast or weak pulse
- lightheadedness
- loss of consciousness
- sudden headache
- sudden loss of coordination
- sudden slurring of speech

Some side effects of levothyroxine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
- Abdominal or stomach cramps
- change in appetite
- crying
- diarrhea
- false or unusual sense of well-being
- fear
- feeling not well or unhappy
- feeling of discomfort
- feeling of warmth
- feeling things are not real
- feelings of suspicion and distrust
- hair loss
- headache
- increased appetite
- mental depression
- muscle weakness
- nervousness
- quick to react or overreact emotionally
- rapidly changing moods
- redness of the face, neck, arms, and occasionally, upper chest
- restlessness
- trouble getting pregnant
- trouble sitting still
- unusual tiredness or weakness
- vomiting
- weight gain
- weight loss
USUAL ADULT DOSE FOR HYPOTHYROIDISM

Oral:
The initial dose is 12.5 to 50 mcg orally once a day. The dosage can be increased in 12.5 to 25 mcg/day increments every 2 to 4 weeks. In older patients or in younger patients with a history of cardiovascular disease, the dosage should be increased in 12.5 to 25 mcg increments every 3 to 6 weeks.

Few patients require doses higher than 200 mcg. Inadequate response to doses higher than 200 mcg is rare and may suggest malabsorption, poor patient compliance and/or drug interactions.

Parenteral: The usual IV or IM dose is 50 to 75% of the oral dose.

USUAL ADULT DOSE FOR TSH SUPPRESSION

Oral:
The initial dose is 50 mcg orally once a day. The dosage may be increased in 25 to 50 mcg increments every 2 to 4 weeks. The typical maintenance dose is 100 to 200 mcg orally once a day.

Parenteral: The usual IV or IM dose is 50 to 75 % of the oral dose.

USUAL ADULT DOSE FOR THYROID SUPPRESSION TEST

Oral: 2.6 mcg/kg/day for 7 to 10 days.

Parenteral: The usual IV or IM dose is 50 to 75% of the oral dose.

USUAL ADULT DOSE FOR MYXEDEMA COMA

Initial dose: 300 to 500 mcg IV bolus administered one time.
Maintenance dose: 75 to 100 mcg IV once a day until the patient can be converted to oral therapy.

USUAL PEDIATRIC DOSE FOR HYPOTHYROIDISM

Congenital hypothyroidism:
Neonatal:
Oral: 10 to 15 mcg/kg/day; if patient is at risk for development of cardiac failure, begin with a lower dose. In severe cases of hypothyroidism (T4 less than 5 mcg/dL), a higher initial dose of 12 to 17 mcg/kg/day may be considered.
IV or IM: 50% to 75% of the oral dose

Oral:
0 to 3 months: 10 to 15 mcg/kg orally once per day; if the infant is at risk for development of cardiac failure use a lower starting dose of approximately 25 mcg/day; if the initial serum T4 is very low (less than 5 mcg/dL) begin treatment at a higher dosage of approximately 50 mcg/day.

3 to 6 months: 8 to 10 mcg/kg or 25 to 50 mcg orally once per day

6 to 12 months: 6 to 8 mcg/kg or 50 to 75 mcg orally once per day

1 to 5 years: 5 to 6 mcg/kg or 75 to 100 mcg orally once per day

6 to 12 years: 4 to 5 mcg/kg or 100 to 125 mcg orally once per day

12 years: 2 to 3 mcg/kg or greater than or equal to 150 mcg orally once per day

Patients in which growth and puberty are complete: 1.7 mcg/kg orally once per day.

For chronic or severe hypothyroidism: 25 mcg orally once per day and increase dosage as needed in increments of 25 mcg every 2 to 4 weeks until the desired effect is achieved.

Comment:
- Hyperactivity in older children may be minimized by starting at one-quarter of the recommended dose and increasing each week by that amount until the full dose is achieved (4 weeks).
-The relative bioavailability between the injection and oral products has not been established. Therefore, caution should be used when switching patients from oral products to the injection as accurate dosing conversion has not been studied.
-A prospective randomized crossover study demonstrated that Synthroid and an AB-rated generic L-T4 are not bioequivalent for patients less than 3 years of age with severe congenital hypothyroidism.

Parenteral:
The usual IV or IM dose is 50 to 75% of the oral dose.

RENAL DOSE ADJUSTMENTS

Data not available

LIVER DOSE ADJUSTMENTS

Data not available

DOSE ADJUSTMENTS

The sudden administration of large doses of levothyroxine in patients with concomitant heart disease is not without cardiovascular risks. The administration of a smaller initial dose may be appropriate.

The relative bioavailability between the injection and oral products has not been established. Therefore, caution should be used when switching patients from oral products to the injection as accurate dosing conversion has not been studied.

Hyperactivity in an older child can be minimized if the starting dose is one-fourth of the recommended full replacement dose, and the dose is then increased on a weekly basis by an amount equal to one-fourth the full-recommended replacement dose until the full recommended replacement dose is attained.

In infants with very low (less than 5 mcg/dL) or undetectable serum T4 concentrations, the recommended initial starting dose is 50 mcg per day.

PRECAUTIONS

Consult WARNINGS section for dosing related precautions.

DIALYSIS

Very little drug is removed by dialysis because T4 is highly protein bound.

OTHER COMMENTS

Levothyroxine should be administered as a single daily dose, preferably one-half to one hour before breakfast.

Levothyroxine should be taken at least 4 hours apart from drugs that are known to interfere with its absorption.

Levothyroxine tablets may be given to infants and children who cannot swallow whole tablets by crushing and suspending the freshly crushed tablet in a small amount of water (5 to 10 mL), breast milk, or non-soybean formula. The suspension should be prepared just prior to administration of the dose and should not be stored for any period of time. The crushed tablet can also be sprinkled over a small amount of food. Foods or formulas containing a large amount of soybean fiber or iron should not be used for administering levothyroxine.
Levothyroxine in capsule form should be swallowed whole and should not be opened, crushed or dissolved in liquid prior to administration.

Reconstituted levothyroxine for injection is preservative free and stable for 4 hours. Any unused product should be discarded. Levothyroxine for injection should not be added to other intravenous fluids. The container closure is not made with natural rubber latex.